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Support for Minimally Invasive Parafascicular Surgery (MIPS) with BrainPath® and Myriad™

(Published/Presented Clinical Data Last Updated 08/29/22)

Preservation of Fascicular Anatomy & White Matter Tract Recovery

  1. Agarwal V, Malcolm JG, Pradilla G, Barrow DL. Tractography for optic radiation preservation in transcortical approaches to intracerebral lesions. Cureus. 2017; 9(9): e1722. https://dx.doi.org/10.7759/cureus.1722
  2. Chakravarthi SS, Zbacnik A, Jennings J, et al. White matter tract recovery following medial temporal lobectomy and selective amygdalophippocampectomy for tumor resection via a ROVOT-m port-guided technique: A case report and review of literature. Interdisciplinary Neurosurgery. 2016; 6:55-61. http://dx.doi.org/10.1016/j.inat.2016.07.004
  3. Zucker, L. Corticospinal tract restoration post parafascicular transulcal subcortical (thalamic) ICH evacuation. Poster #1450 presented at: 2016 Congress of Neurological Surgeons Annual Meeting; September 24-28, 2016; San Diego, CA. http://2016.cns.org/posterbrowser.aspx

Vascular Applications of MIPS

Minimally Invasive Parafascicular Surgery for Intracerebral Hemorrhage

  1. Falcone J, Chen JW. Early minimally invasive parafascicular surgery for evacuation of spontaneous intracerebral hemorrhage in the setting of computed tomography angiography spot sign: a case series. Operative Neurosurgery. 2022; 22(3):123-130. https://dx.doi.org/10.1227/ONS.0000000000000078
  2. Kellner CP, Schupper AJ, Mocco J. Surgical evacuation of intracerebral hemorrhage: the potential importance of timing. Stroke. 2021; 52:3391-3398. https://doi.org/10.1161/STROKEAHA.121.032238
  3. Carpenter AB, Lara-Reyna J, Hardigan T, Ladner T, Kellner C, Yaeger K. Use of emerging technologies to enhance the treatment paradigm for spontaneous intraventricular hemorrhage. Neurosurgical Review. 2021; AOP. https://doi.org/10.1007/s10143-021-01616-z
  4. Liang B, Zhang Y, Nguyen AV, Huang JH, Feng D. Surgical evacuation of intracerebral hemorrhage using DTT-guided parafascicular BrainPath/Myriad technique. Brain Hemorrhages. 2021; AOP. https://doi.org/10.1016/j.hest.2021.06.002
  5. O’Carroll CB, Brown BL, Freeman WD. Intracerebral hemorrhage: a common yet disproportionately deadly stroke subtype. Thematic Review on Neurovascular Diseases. 2021; 96(6):1639-1654. https://doi.org/10.1016/j.mayocp.2020.10.034
  6. Hannah TC, Kellner R, Kellner CP. Minimally Invasive Intracerebral Hemorrhage Evacuation Techniques: A Review. Diagnostics. 2021; 11(3):576. https://doi.org/10.3390/diagnostics11030576
  7. Vitt JR, Sun CH, Le Roux PD, Hemphill 3ʳᵈ JC. Minimally invasive surgery for intracerebral hemorrhage. Curr Opin Crit Care. 2020 April; 26(2):129-136. https://doi.org/10.1097/MCC.0000000000000695
  8. Chakravarthi SS, Lyons L, Orozco AR, Verhey L, Mazaris P, Zacharia J, et al. Combined decompressive hemicraniectomy (DHC) and port-based minimally-invasive Parafascicular surgery (MIPS) for the treatment of subcortical intracerebral hemorrhage: Case series, Technical note, and Review of literature. World Neurosurgery. 2020; Journal Pre-Proof. https://doi.org/10.1016/j.wneu.2020.11.130
  9. Achey R, Moore N, Bain M. Use of 11mm BrainPath endoport in minimally invasive hematoma evacuation: a case report. Interdisciplinary Neurosurgery. 2021; 100945:AOP. https://doi.org/10.1016/j.inat.2020.100945
  10. Phillips VL, Roy AK, Ratcliff J, Pradilla G. Minimally invasive Parafascicular surgery (MIPS) for spontaneous intracerebral hemorrhage compared to medical management: a case series comparison for a single institution. Stroke Research and Treatment. 2020; Article ID 6503038. https://doi.org/10.1155/2020/6503038
  11. Das S, Pradilla G, Khalessi A. Minimally invasive surgery for patients with spontaneous intracerebral hemorrhage: a book reopened. SN Comprehensive Clinical Medicine. 2020; 2:640-643. https://doi.org/10.1007/s42399-020-00287-z
  12. Rutkowski M, Song I, Mack W, Zada G. Outcomes after minimally invasive Parafascicular surgery for intracerebral hemorrhage: a single-center experience. World Neurosurgery. 2019; 132:e520-e528. https://doi.org/10.1016/j.wneu.2019.08.087
  13. Shao J, Witek A, Borghel-Razavi H, Bain M, Recinos PF. Endoscopic evacuation of intracerebral hematoma utilizing a side-cutting aspiration device. Operative Neurosurgery. 2019. https://dx.doi.org/10.1093/ons/opz309
  14. Pan J, Chartrain AG, Scaggiante J, Spiotta AM, Tang Z, Wang W, et al. A compendium of modern minimally invasive intracerebral hemorrhage evacuation techniques. Operative Neurosurgery. 2019. https://dx.doi.org/10.1093/ons/opz308
  15. Marenco-Hillembrand L, Suarez-Meade P, Garcia HR, Murguia-Fuentes R, Middlebrooks EH, Kangas L, et al. Minimally invasive surgery and transsulcal parafascicular approach in the evacuation of intracerebral haemorrhage. Stroke and Vascular Neurology. 2019; 0. https://dx.doi.org/10.1136/svn-2019-000264
  16. Song I, Rutkowski M, Mack W, Zada G. Clinical and radiographic outcomes following intracerebral hematoma evacuation via BrainPath-assisted minimally invasive craniotomy. Poster #1044 presented at: 2019 American Association of Neurological Surgeons Annual Meeting; April 13-17, 2019; San Diego, CA. https://360.aans.org/AppSearch/Eposter?eventid=48888&itemid=EPOSTER&propid=45330
  17. Griessenaurer CJ, Medin C, Goren O, Schirmer C. Image-guided minimally invasive evacuation of intracerebral hematoma: a matched cohort study comparing endoscopic and tubular exoscopic systems. Poster #1084 presented at: 2019 American Association of Neurological Surgeons Annual Meeting; April 13-17, 2019; San Diego, CA. https://360.aans.org/AppSearch/Eposter?eventid=48732&itemid=EPOSTER&propid=41281
  18. Bain M, Witek A, Moore N, Pradilla G. Targeting spot sign in intracerebral hemorrhage with NICO BrainPath minimally invasive parafascicular surgery to prevent hematoma expansion. Oral Presentation O-106 presented at: 2019 World IntraCranial Hemorrhage Conference; May 19-21, 2019; Granada, Spain. https://worldich.org/2019/scientific-information/abstract-e-book#.XSOGGOhKjnY
  19. Verhey LH, Lyoncs L, Mazaris P, Zachariah J, Singer JA. Hemicraniectomy with minimally invasive evacuation for intracranial hematoma: a novel hybrid technique. Abstract SO-065 presented at: 2019 World IntraCranial Hemorrhage Conference; May 19-2019; Granada, Spain. https://worldich.org/2019/scientific-information/abstract-e-book#.XSOGGOhKjnY
  20. Kon Kam King N. Initial experience with minimally invasive parafascicular surgical approach for evacuation of supratentorial intracerebral hemorrhage. Oral Presentation SO-003 presented at: 2019 World IntraCranial Hemorrhage Conference; May 19-21, 2019; Granada, Spain. https://worldich.org/2019/scientific-information/abstract-e-book#.XSOGGOhKjnY
  21. Kon Kam King N. Minimally invasive parafascicular surgery for supratentorial intracerebral hemorrhage. Oral Presentation O-109 presented at: 2019 World IntraCranial Hemorrhage Conference; May 19-21, 2019; Granada, Spain. https://worldich.org/2019/scientific-information/abstract-e-book#.XSOGGOhKjnY
  22. Vargas J, Spiotta AM, Turner RD. Spontaneous Intracerebral Hemorrhage. Management of Cerebrovascular Disorders. 2019; Chapter 24: 381-395. https://doi.org/10.1007/978-3-319-99016-3_24
  23. Ratcliff J, Hall A, Jankowitz B, Molyneaux B, Bain M, Gomes J, et al. Clinical Trial Update: Early Minimally Invasive Removal of Intracerebral Hemorrhage (ENRICH) Clinical Trial. Presented at: 2019 International Stroke Conference; February 6-8, 2019; Honolulu, HI. https://eventpilotadmin.com/web/page.php?page=Inthtml&project=ISC19&id=1659
  24. Griessenaurer C, Medin C, Goren O, Schirmer CM. Image-guided, minimally-invasive evacuation of intracerebral hematoma: a matched cohort study comparing the endoscopic and tubular exoscopic systems. Cureus. 2019; 10(11): e3569. https://doi.org/10.7759/cureus.3569
  25. Bhatia K, Hepburn M, Ziu E, Siddiq F, Quershi AI. Modern approaches to evacuating intracerebral hemorrhage. Current Cardiology Reports. 2018; 20:132. http://dx.doi.org/10.1007/s11886-018-1078-4
  26. Cusack TJ, Carhuapoma JR, Ziai WC. Update on the treatment of spontaneous intraparenchymal hemorrhage: medical and interventional management. Current Treatment Options in Neurology. 2018; 20:1. http://dx.doi.org/10.1007/s11940-018-0486-5
  27. Cavallo C, Zhao X, Abou-Al-Shaar H, Weiss M, GandhiS, Belykh E, et al. Minimally invasive approaches for the evacuation of intracerebral hemorrhage: a systematic review. Journal of Neurosurgical Sciences. 2018; 62(6):718-733. http://www.dx.doi.org/10.23736/S0390-5616.18.04557-5
  28. Vargas J, Spiotta AM, Turner RD. Surgical Treatment of Intracerebral Hemorrhage. Intracerebral Hemorrhage Therapeutics. 2018; Chapter 6: 81-93. https://doi.org/10.1007/978-3-319-77063-5_6
  29. Sindelar BD, Patel V, Chowdhry S, Bailes JE. A case report in hemorrhagic stroke: a complex disease process and requirement for a multimodal treatment approach. Cureus. 2018; 10(7): e2976. http://www.dx.doi.org/10.7759/cureus.2976
  30. Scaggiante J, Zhang X, Mocco J, Kellner CP. Minimally invasive surgery for intracerebral hemorrhage: an updated meta-analysis of randomized controlled trials. Stroke. 2018;49:AOP. http://dx.doi.org/10.1161/STROKEAHA.118.020688.
  31. Abunimer AM, Abou-Al-Shaar H, Cavallo C, Mahan MA, Labib MA. Minimally invasive approaches for the management of intraventricular hemorrhage. Journal of Neurosurgical Sciences. 2018; 62(6):734-744. http://dx.doi.org/10.23736/S0390-5616.18.04511-3
  32. Ratcliff JJ, Hall AJ, Jankowitz BT, Molyneaux BJ, Bain MD, Gomes JA, et al. Clinical trial update: early minimally invasive removal of intracerebral hemorrhage (ENRICH) clinical trial. Presented at: 2018 International Stroke Conference; January 24-26, 2018; Los Angeles, CA. https://professional.heart.org/professional/EducationMeetings/MeetingsLiveCME/InternationalStrokeConference/UCM_316939_Archive-International-Stroke-Conference.jsp
  33. Ratcliff JJ, Hall AJ, Saville BR, Phillips VL, Sekerak P, Lewis RJ, et al. Trial design, methods, and rationale for the early minimally invasive removal of intracerebral hemorrhage (ENRICH) clinical trial. Presented at: 2017 Neurocritical Care Society Annual Meeting; Hilton Waikoloa Village, HI.
  34. Ding D, Przybylowski CJ, Starke RM, Crowley W, Liu KC. Eyebrow incision for surgical evacuation of a lobar intracerebral hematoma with a novel endoport system. Journal of Cerebrovascular and Endovascular Neurosurgery. 2017; 19(2):101-105. https://doi.dx.org/10.7461/jcen.2017.19.2.101
  35. Labib MA, Shah M, Kassam AB, Young R, Zucker L, Maioriello A, et al. The safety and feasibility of image-guided BrainPath-mediated transsulcul hematoma evacuation: a multicenter study. Neurosurgery. 2017; 80(4):515-524. http://dx.doi.org/10.1227/NEU.0000000000001316
  36. Sujijantarat N, El Tecle N, Pierson M, Urquiaga JF, Quadri NF, Ashour AM, et al. Trans-sulcal endoport-assisted evacuation of supratentorial intracerebral hemorrhage: initial single-institution experience compared to matched medically managed patients and effect on 30-day mortality. Operative Neurosurgery. 2017; 14(5):524-531. https://doi.org/10.1093/ons/opx161
  37. Lang M, Witek AM, Moore NZ, Bain MD. Clinical Outcomes of Patients Undergoing BrainPath-assisted Evacuation of Intracerebral Hemorrhage. Abstract presented at: 2017 International Stroke Conference; February 22-24, 2017; Houston, TX. https://aha.scientificposters.com/epsAbstractAHA.cfm?id=1
  38. Bauer AM, Rasmussen PA, Bain MD. Initial single-center technical experience with the BrainPath system for acute intracerebral hemorrhage evacuation. Operative Neurosurgery. 2017; 13(1):69-76. https://academic.oup.com/ons/article-abstract/13/1/69/2608027?redirectedFrom=fulltext
  39. Ziai W, Nyquist P, Hanley DF. Surgical strategies for spontaneous intracerebral hemorrhage. Seminars in Neurology. 2016; 36:261-268. http://dx.doi.org/10.1055/s-0036-1582131
  40. Fiorella D, Arthur A, Bain M, Mocco J. Minimally invasive surgery for intracerebral and intraventricular hemorrhage. Stroke. 2016; 47:1399-1406. http://dx.doi.org/10.1161/STROKEAHA.115.011415
  41. Przybylowski CJ, Ding D, Starke RM, Crowley RW, Liu KC. Endoport-assisted surgery for the management of spontaneous intracerebral hemorrhage. Journal of Clinical Neuroscience. 2015; 22(11): 1727-1732. http://dx.doi.org/10.1016/j.jocn.2015.05.015
  42. Ding D, Przybylowski CJ, Starke, RM, et al. A minimally invasive anterior skull base approach for evacuation of a basal ganglia hemorrhage. Journal of Clinical Neuroscience. 2015; 22(11): 1816-1819. http://dx.doi.org/10.1016/j.jocn.2015.03.052
  43. Chen J, Tran K, Dastur C, Stradling D, Yu W. The use of the BrainPath stereotactic guided surgery for the removal of spontaneous intracerebral hemorrhage: a single institutional experience. Abstract presented at: 2015 NeuroCritical Care Society Meeting; October 7-10, 2015; Scottsdale, AZ. http://link.springer.com/article/10.1007/s12028-015-0193-y
  44. Kulwin C, Rodgers R, Shah M. Preliminary experience with evacuation of intracerebral hemorrhage via a minimally invasive parafascicular technique. Presented at: 2015 Neurosurgical Society of America Annual Meeting; April 2015.
  45. Labib M, Britz G, Young R, Zucker L, Shah M, Kulwin CG, et al. The safety and efficacy of image-guided trans-sulcal radial corridors for hematoma evacuation: a multicenter study. Late breaking oral presentation LB12 at: 2015 International Stroke Conference; February 11-13, 2015; Nashville, TN. http://my.americanheart.org/idc/groups/ahamah-public/@wcm/@sop/@scon/documents/downloadable/ucm_471665.pdf
  46. Britz G, Kassam AB, Labib M, Young R, Zucker L, Maioriello A, et al. Minimally invasive subcortical parafascicular access for clot evacuation: a paradigm shift. Poster # MP120 presented at: 2015 International Stroke Conference; February 11-13, 2015; Nashville, TN. http://stroke.ahajournals.org/content/46/Suppl_1/AWMP120.short?rss=1
  47. Ritsma B, Kassam AB, Dowlatshahi D, Nguyen T, Stotts G. Minimally invasive subcortical parafascicular transsulcal access for clot evacuation (Mi SPACE) for intracerebral hemorrhage. Case Rep Neurol Med. 2014; 2014(102307): 4 pages. http://dx.doi.org/10.1155/2014/102307
  48. Ghinda DC, Bafaquh M, Labib M, Kumar R, Agbi CB, Kassam AB. A Transulcul Exoscopic radial corridor approach for the management of primary intracranial hemorrhage. Poster #1621 presented at: 2013 Congress of Neurological Surgeons Annual Meeting; October 19-23, 2013; San Francisco, CA. http://2013.cns.org/posterbrowser.aspx

Minimally Invasive Parafascicular Surgery for Traumatic Intracerebral Hemorrhage

  1. Tran DKT, Xu J, Shah I, Tran P, Chen J. Cerebral microdialysis as a marker of perihematomal edema in spontaneous and traumatic intracranial hemorrhages. Poster #1889 presented at: 2019 American Association of Neurological Surgeons Annual Meeting; April 13-17, 2019; San Diego, CA. https://360.aans.org/AppSearch/Eposter?eventid=48888&itemid=EPOSTER&propid=45593
  2. Chen JW, Tran DK, Soldevilla F, Dickinson L, Adler D. Multi-center experience treating traumatic intracerebral hemorrhages with minimally invasive parafascicular techniques. Poster #1929 presented at: 2019 American Association of Neurological Surgeons Annual Meeting; April 13-17, 2019; San Diego, CA. https://360.aans.org/AppSearch/Eposter?eventid=48888&itemid=EPOSTER&propid=45615
  3. Chen JW, Paff MR, Abrams-Alexandru D, Kaloostian SW. Decreasing the cerebral edema associated with traumatic intracerebral hemorrhages: use of a minimally invasive technique. In: RL Applegate et al (eds), Brain Edema XVI: Translate Basic Science into Clinical Practice, Acta Neurochirurgica Supplement. 2016; 121:279-284. doi: 10.1007/978-3-319-18497-5_48. https://www.ncbi.nlm.nih.gov/pubmed/26463961
  4. Chen J, Kaloostian SW. Use of minimally invasive techniques under austere circumstances for the urgent resection of subcortical intracerebral hemorrhages. Poster #0075 presented at: 12th Annual Conference of the Society for Brain Mapping and Therapeutics; March 6-8, 2015.

Minimally Invasive Parafascicular Surgery for Other Vascular Abnormalities

  1. Alexopoulos G, Prim M, Khan M, Quadri N, Urquiaga FJ, El Tecle N, et al. Minimally Invasive Evacuation of Severe Intraventricular Hemorrhage using the BrainPath Endoport-Assisted Microsurgical System. World Neurosurgery. 2019. https://doi.org/10.1016/j.wneu.2019.10.135
  2. Eichberg DG, Di L, Shah AH, Ivan ME, Komotar R, Starke RM. Use of tubular retractors for minimally invasive resection of deep-seated cavernomas. Operative Neurosurgery. 2019. https://dx.doi.org/10.1093/ons/opz184
  3. O’Connor KP, Strickland AE, Bohnstedt BN. A contralateral transventricular approach for microsurgical clip ligation of a ruptured intrathalamic aneurysm. Journal of Clinical Neuroscience. 2019. AOP. https://dx.doi.org/10.1016/j.jocn.2019.07.028
  4. Eichberg D, Di L, Ivan M, Komotar R, Starke R. Minimally invasive transtubular approach for resection of deep-seated cavernomas. Poster #1143 presented at: 2019 American Association of Neurological Surgeons Annual Meeting; April 13-17, 2019; San Diego, CA. https://360.aans.org/AppSearch/Eposter?eventid=48888&itemid=EPOSTER&propid=45401
  5. Goren O, Griessenauer CJ, Bohan CO, Berry CM, Schirmer CM. Minimally invasive parafascicular surgery for resection of cerebral cavernous malformations utilizing image-guided BrainPath system. Operative Neurosurgery. AOP2018. http://www.dx.doi.org/10.1093/ons/opy389
  6. Witek AM, Moore NZ, Sebai MA, Bain MD. BrainPath-mediated resection of a ruptured subcortical arteriovenous malformation. Operative Neurosurgery. 2018; 15(1):32-38. http://dx.doi.org/10.1093/ons/opx186
  7. Chen CJ, Caruso J, Starke RM, et al. Endoport-assisted microsurgical treatment of a ruptured periventricular aneurysm. Case Rep Neurol Medicine. 2016; 2016(8654262): 4 pages. http://dx.doi.org/10.1155/2016/8654262
  8. Amenta PS, Dumont AS, Medel R. Resection of a left posterolateral thalamic cavernoma with the Nico BrainPath sheath: case report, technical note, and review of the literature. Interdisciplinary Neurosurgery: Advanced Techniques and Case Management. 2016; 5:12-17. http://dx.doi.org/10.1016/j.inat.2016.03.006
  9. Scranton RA, Fung SH, Britz GW. Transulcal parafascicular minimally invasive approach to deep and subcortical cavernomas: technical note. Journal of Neurological Surgery. 2016; 125(6): 1360-1366. http://dx.doi.org/10.3171/2015.12.JNS152185
  10. Ding D, Starke R, Crowley R, Liu K. Endoport-assisted microsurgical resection of cerebral cavernous malformations. Journal of Clinical Neuroscience. 2015; 22(6):1025-1029. http://dx.doi.org/10.1016/j.jocn.2015.01.004

Tumor Clinical Data

Minimally Invasive Parafascicular Surgery or Biopsy for Primary and Secondary Tumors, Cysts, and Lesions

  1. Lavrador JP, Oviedova A, Pereira N, Patel S, Rajwani KM, Sekhon P, et al. Minimally invasive approach to a deep-seated motor eloquent brain tumour: a technical note. Journal of Surgical Case Reports. 2022; 1:1-4. https://doi.org/10.1093/jscr/rjab611
  2. Sweeney KJ, Amoo M, Kilbride R, Jallo GI, Javadpour M. Exoscope aided trans-sulcal minimally invasive parafascicular resection of a paediatric brainstem pilocytic astrocytoma using a tubular retractor system. British Journal of Neurosurgery. 2021. https://doi.org/10.1080/02688697.2021.1967880
  3. Strickland BA, Brunswick A, Zada G. Exoscopic to endoscopic channel-based trans-sulcal resection of a third ventricular cavernous malformation: technical case illustration. World Neurosurgery. 2021; 148:66. https://doi.org/10.1016/j.wneu.2021.01.007
  4. Rennert RC, Khani M, Thomas K, Morris TW, Rodriguez A, Day JD. Transsulcal parafascicular brain path-assisted approach to subcortical lesions: 2-dimensional operative video. Surgical Neurology International. 2021; 12:107. DOI: 10.25259/SNI_776_2020
  5. Marenco-Hillembrand L, Prevatt C, Suarez-Meade P, Ruiz-Garcia H, Quinones-Hinojosa A, Chaichana KL. Minimally invasive surgical outcomes for deep-seated brain lesions treated with different tubular retraction systems: a systematic review and meta-analysis. World Neurosurgery. 2020; 143(3):537-545. https://doi.org/10.1016/j.wneu.2020.07.115
  6. Belzberg M, Mahapatra S, Perdomo-Pantoja A, Chavez F, Morrison K, Xion KT, et al. Minimally invasive therapeutic ultrasound: Ultrasound-guided ultrasound ablation in neuro-oncology. Ultrasonics. 2020; 108:106210.
  7. Grewel SS, ReFaey K, Ganaha S, Reimer R, Quinones-Hinojosa A, Wharen RE. Advances in Surgical Approaches to Supratentorial Deep-Seated Lesions. Modern Surgical Approaches to Intrinsic Brain Tumors. 2019; Chapter 23: 393-404. https://doi.org/10.1016/B978-0-12-811783-5.00027-6
  8. Gianaris T, Monaco G, Weyhenmeyer J, Shah M. Diffusion tensor imaging in neuronavigation to guide a trans-sulcal approach to glioma in awake craniotomy. Poster #1811 presented at: 2019 American Association of Neurological Surgeons Annual Meeting; April 13-17, 2019; San Diego, CA. https://360.aans.org/AppSearch/Eposter?eventid=48888&itemid=EPOSTER&propid=45689
  9. Zammar SG, Cappelli J, Zacharia BE. Utility of tubular retractors augmented with intraoperative ultrasound in the resection of deep-seated brain lesions: technical note. Cureus. 2019; 11(3): e4272. https://doi.org/10.7759/cureus.4272
  10. Gassie K, Alvarado-Estrada K, Bechtle P, Chaichana KL. Surgical management of deep-seated metastatic brain tumors using minimally invasive approaches. Journal of Neurological Surgery-A. 2019; e-FIRST. https://doi.org/10.1055/s-0038-1676575
  11. Bander ED, Jones SH, Pisapia D, Magge R, Fine H, Schwartz TH, Ramakrishna R. Tubular brain tumor biopsy to improve diagnostic yield for subcortical lesions. Journal of NeuroOnc. AOP2018. http://www.dx.doi.org/10.1007/s11060-018-03014-w
  12. Akbari SHA, Sylvester PT, Kulwin C, Shah MV, Somasundaram A, Kamath AA, et al. Initial experience using intraoperative magnetic resonance imaging during a trans-sulcal tubular retractor approach for the resection of deep-seated brain tumors: a case series. Operative Neurosurgery. AOP2018. https://doi.org/10.1093/ons/opy108
  13. Bakhsheshian J, Strickland BA, Jackson C, Chaichana KL, Young R, Pradilla G, et al. Multicenter investigation of channel-based subcortical trans-sulcal exoscopic resection of metastatic brain tumors: a retrospective case series. Operative Neurosurgery. AOP2018. https://doi.org/10.1093/ons/opy079
  14. Eichberg DG, Buttrick SS, Sharaf JM, Snelling BM, Shah AH, Ivan ME, et al. Use of tubular retractor for resection of colloid cysts: single surgeon experience and review of literature. Operative Neurosurgery. AOP2018. http://www.dx.doi.org/10.1093/ons/opy249
  15. Marenco-Hillembrand L, Alvarado-Estrada K, Chaichana KL. Contemporary surgical management of deep-seated metastatic brain tumors using minimally invasive approaches. Frontiers in Oncology. 2018; 8(588). http://www.dx.doi.org/10.3389/fonc.2018.00558
  16. Mampre D, Bechtle A, Chaichana KL. Minimally invasive resection of intra-axial posterior fossa tumors using tubular retractors. World Neurosurgery. 2018; 119:e1016-e1020. https://doi.org/10.1016/j.wneu.2018.08.049
  17. Iyer R, Chaichana KL. Minimally invasive resection of deep-seated high-grade gliomas using tubular retractors and exoscopic visualization. J Neurol Surg A Cent Eur Neurosurg. 2018; 79(04):330-336. https://doi.org/10.1055/s-0038-1641738
  18. Eichberg DG, Buttrick S, Brusko GD, Ivan M, Starke RM, Komotar RJ. Use of tubular retractor for resection of deep-seated cerebral tumors and colloid cysts: single surgeon experience and review of literature. World Neurosurgery. 2018; 112:e50-e60. https://doi.org/10.1016/j.wneu.2017.12.023
  19. Gassie K, Wijesekera O, Chaichana KL. Minimally invasive tubular retractor-assisted biopsy and resection of subcortical intra-axial gliomas and other neoplasms. Journal of Neurosurgical Sciences. 2018; 62(6):682-689. http://dx.doi.org/10.23736/S0390-5616.18.04466-1
  20. Day JD. Transsulcal parafascicular surgery using BrainPath for subcortical lesions. Neurosurgery. 2017; 64(Suppl 1):151-156. http://dx.doi.org/10.1093/neuros/nyx324
  21. Buttrick SS, Shah AH, Basil GW, Komotar RJ. The future of cranial neurosurgery – adapting new approaches. Neurosurgery. 2017; 64(CN1):144-150. http://dx.doi.org/10.1093/neuros/nyx214
  22. Chen Y, Omay SB, Sathwik SR, Liang B, Almeida JP, Ruiz-Trevino AS, et al. Transtubular excisional biopsy as a rescue for a non-diagnostic stereotactic needle biopsy – case report and literature review. Acta Neurochir. 2017; 159(9):1589-1595. https://dx.doi.org/10.1007/s00701-017-3260-7
  23. Jackson C, Gallia GL, Chaichana KL. Minimally invasive biopsies of deep-seated brain lesions using tubular retractors under exoscopic visualization. Journal of Neurological Surgery, A. 2017; 78(6):588-594. https://doi.org/10.1055/s-0037-1602698
  24. Somasundaram A, Evans J, Shah M, Asbari SH, Chicoine M, Kulwin C. Resection of deep-seated intrinsic brain tumors using a novel combination of a minimally invasive tubular brain retraction system, high resolution exoscope visualization, and high field intraoperative magnetic resonance imaging (iMRI). Poster #2081 presented at: 2016 Congress of Neurological Surgeons Annual Meeting; September 24-28, 2016; San Diego, CA. http://latebreaking16.cns.org/posterbrowser.aspx
  25. Habboub G, Sharma M, Barnett GH, Mohammadi AM. A novel combination of two minimally invasive surgical techniques in the management of refractory radiation necrosis: Technical note. Journal of Clinical Neuroscience. 2016; 35:117-121. https://dx.doi.org/10.1016/j.jocn.2016.09.020
  26. Nagatani K, Takeuchi S, Feng D, Mori K, Day JD. High definition exoscope system for microneurosurgery: Use of an exoscope in combination with tubular retraction and frameless neuronavigation for microsurgical resection of deep brain lesions. Neurological Surgery, Japan. 2015; 43(7): 611-617. http://medicalfinder.jp/doi/abs/10.11477/mf.1436203086
  27. Labib M, Young RL, Rovin RA, Day JD, Eliyas JK, Bailes JE. The safety and efficacy of diffusion tensor imaging (DTI)- guided Transulcal radial tubular corridors to subcortical neoplasms: A multicenter study. Abstract presented at: 2015 Congress of Neurological Surgeons Annual Meeting; September 26-30, 2015; New Orleans, LA. http://2015.cns.org/posterbrowser.aspx
  28. Eliyas JK, Bailes J. Early experience with trans-sulcal parafascicular Exoscopic resection of supratentorial brain tumors. Neuro Oncol. 2014; 16(5):v161. https://dx.doi.org/10.1093/neuonc/nou265.13
  29. Rovin R, Kassam AB. Minimally invasive surgical resection of subcortical tumors using the six pillars system. Poster #ST-029 presented at: 18th Annual Meeting of the Society for Neuro-Oncology; November 21-24, 2013; San Francisco, CA. http://soc-neuro-onc.conference-services.net/reports/template/onetextabstract.xml?xsl=template/onetextabstract.xsl&conferenceID=3676&abstractID=760212

Minimally Invasive Parafascicular Surgery for Intraventricular Tumors, Cysts, and Lesions

  1. Lin M, Bakhsheshian J, Strickland B, Rennert RC, Chen JW, Van Gompel JJ, et al. Navigable channel-based trans-sulcal resection of third ventricular colloid cysts: a multicenter retrospective case series and review of the literature. World Neurosurgery. 2019. https://doi.org/10.1016/j.wneu.2019.09.134
  2. Lin M, Bakhsheshian J, Strickland B, Rennert RC, Chu RM, Chaichana KL, et al. Exoscopic resection of atrial intraventricular meningiomas using a navigation-assisted channel-based trans-sulcal approach: Case series and literature review. Journal of Clinical Neuroscience. 2019. https://doi.org/10.1016/j.jocn.2019.10.017
  3. Chakravarthi SS, Kassam AB, Fukui BM, Monroy-Sosa A, Rothong N, Cunningham J, et al. Awake surgical management of third ventricular tumors: a preliminary safety, feasibility, and clinical applications study. Operative Neurosurgery. 2019. https://doi.org/10.1093/ons/opy405
  4. Vigneswaran K, Pradilla G. Tubular retractors for intraventricular tumors. Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors. 2019; Chapter 27: 451-463. https://doi.org/10.1016/B978-0-12-811783-5.00027-6
  5. Eliyas JK, Glynn R, Kulwin CG, et al. Minimally-invasive trans-sulcal resection of Intra-ventricular and Peri-ventricular lesions through a tubular retractor system: Multi-centric experience and results. World Neurosurgery. 2016; 90: 556-564. http://dx.doi.org/10.1016/j.wneu.2015.12.100
  6. Alzate J, Young R, Rovin R. A novel minimally invasive approach for the resection of intraventricular tumors. Neuro Oncol (2014) 16 (suppl 5):v127. http://www.dx.doi.org/10.1093/neuonc/nou260.3

Multiple Disease State Data

  1. Achey RL, Pranay S, Kashkoush A, Kondylis E, Moore N, Bain M. Novel use of the Aurora Surgiscope for minimally invasive resection of intraparenchymal lesions: a case series. Operative Neurosurgery. 2022; 23(3):182-187. https://doi.org/10.1227/ons.0000000000000292
  2. Cartwright MM, Sekerak P, Mark J, Bailes J. Use of a novel navigable tubular retractor system in 1826 minimally invasive Parafascicular surgery (MIPS) cases involving deep-seated brain tumors, hemorrhages and malformations. Interdisciplinary Neurosurgery. 2021; 23:100919. https://doi.org/10.1016/j.inat.2020.100919
  3. Echeverry N, Mansour S, MacKinnon G, Jaraki J, Shapiro S, Snelling B. Intracranial tubular retractor systems: a comparison and review of the literature of the BrainPath, Vycor, and METRx tubular retractors in the management of deep brain lesions. World Neurosurgery. 2020; 143:134-146. https://doi.org/10.1016/j.wneu.2020.07.131
  4. Eichberg DG, Di L, Shah AH, Luther EM, Jackson C, Marenco-Hillembrand L, et al. Minimally invasive resection of intracranial lesions using tubular retractors: a large, multi-surgeon, multi-institutional series. JNeuro-Oncology. 2020; 149:35-44. https://doi.org/10.1007/s11060-020-03500-0
  5. Mansour S, Echeverry N, Shapiro S, Snelling B. The Use of BrainPath Tubular Retractors in the Management of Deep Brain Lesions: A Review of Current Studies. World Neurosurgery. 2020. https://doi.org/10.1016/j.wneu.2019.08.218
  6. Cartwright M, Alzate J. Experiential summary of 286 cases of brain surgery in older adults using a navigable tubular retractor system for the trans-sulcal removal of deep-seated brain tumors and vascular hemorrhages, malformations and lesions Poster presented at: 2018 American Association of Neurological Surgeons Annual Meeting; April 28-May 2, 2018; New Orleans, LA. https://www.aans.org/Online-Program/Eposter?eventid=48732&itemid=EPOSTER&propid=42649
  7. Cartwright M, Hagerman E, Dougherty B, Mark J. Stepwise development and commercialization of a modern navigable tubular access assembly system through a multidisciplinary startup-academic collaboration. Poster presented at: Poster presented at: 2018 American Association of Neurological Surgeons Annual Meeting; April 28-May 2, 2018; New Orleans, LA. https://www.aans.org/Online-Program/Eposter?eventid=48732&itemid=EPOSTER&propid=42655
  8. Polster SP, Cartwright MM, Patel V, Bailes JE. Experiential summary of 1032 cases of adult brain surgery using a navigable trans-sulcal tubular retractor device for the removal of deep-seated brain lesions. Poster presented at: 2017 Congress of Neurological Surgeons Annual Meeting; October 7-11, 2017; Boston, MA. https://www.cns.org/education/browse-type/abstracts-and-posters
  9. Gonen L, Chakravarthi SS, Monroy-Sosa A, Celix JM, Kojis N, Singh M, et al. Initial experience with a robotically operated video optical telescopic-microscope in cranial neurosurgery: feasibility, safety, and clinical applications. Neurosurgical Focus. 2017; 42(5):E9. https://dx.doi.org/10.3171/2017.3.FOCUS1712
  10. Kassam AB, Labib MA, Bafaquh M, et al. Part II: an evaluation of an integrated systems approach using diffusion-weighted, image-guided, Exoscopic-assisted, transulcal radial corridors. Innovative Neurosurgery. 2015; 3(1-2):25-33. http://dx.doi.org/10.1515/ins-2014-0012
  11. Kassam AB, Labib MA, Bafaquh M, et al. Part I: the challenge of functional preservation: an integrated systems approach using diffusion-weighted, image-guided, Exoscopic-assisted, transulcal radial corridors. Innovative Neurosurgery. 2015; 3(1-2):5-23. http://dx.doi.org/10.1515/ins-2014-0011
  12. Kulwin CG, Shah MV. Minimally invasive parafascicular approach to deep cerebral lesions: initial Indiana University experience. Presented at: 2014 Neurosurgical Society of America Annual Meeting; June 2014.
  13. Labib M, Ghinda D, Bafaquh M, Kumar R, Agbi C, Kassam AB. The diffusion tensor imaging (DTI) guided Transulcul Exoscopic radial corridor approach for the resection of lesions in the sensorimotor area. Poster #1598 presented at: 2013 Congress of Neurological Surgeons Annual Meeting; October 19-23, 2013; San Francisco, CA. http://2013.cns.org/posterbrowser.aspx.

Pediatric Applications

  1. Orozco AR, Verhey LH, Chakravarthi S, Lyons L, Madura C, Bercu MM, et al. Minimally invasive transsulcal Parafascicular resection of subcortical lesions in pediatric patients: a preliminary retrospective case series study. Neurosurgery. 2020; 65(Supp_1):nyaa447_586. https://doi.org/10.1093/neuros/nyaa447_586
  2. Chakravarthi SS, Lyons L, Bercu M, Singer JA. Minimally invasive Parafascicular surgical approach for the management of a pediatric third ventricular ependymoma: case report and review of literature. World Neurosurgery. 2020; 141:311-317. https://doi.org/10.1016/j.wneu.2020.04.201
  3. Chang KE, Botros J, Kiehna E. Minimally invasive resection of rolandic cavernomas in children using a novel navigable tubular retractor system. Poster #1316 presented at: 2019 American Association of Neurological Surgeons Annual Meeting; April 13-17, 2019; San Diego, CA. https://360.aans.org/AppSearch/Eposter?eventid=48888&itemid=EPOSTER&propid=44958
  4. Kiehna EN, Young RL. Minimally invasive resection of subcortical pediatric brain tumors and vascular malformations using a novel navigable tubular retractor system. Poster PF-091 presented at: 46th Annual Meeting of International Society for Pediatric Neurosurgery. October 7-11, 2018; Tel Aviv, Israel.
  5. Chang K, Botros J, Kiehna EN. Minimally invasive resection of subcortical pediatric brain tumors and vascular malformations using a novel navigable tubular retractor system. Poster 639 presented at: 2018 Congress of Neurological Surgeons Meeting, October 8-10, 2018; Houston, TX.
  6. Chang K, Botros J, Kiehna EN, Krieger MD. Minimally invasive resection of rolandic cavernomas in children using a novel navigable tubular retractor system. Poster 661 presented at: 2018 Congress of Neurological Surgeons Meeting, October 8-10, 2018; Houston, TX.
  7. Young RA, Cartwright M, Kiehna EN. Minimally invasive resection of subcortical pediatric brain tumors and vascular malformations using a novel navigable tubular retractor system. Presented at: 2017 AANS/CNS Pediatric Section Meeting; November 29-December1, 2017; Houston, TX.
  8. Kiehna EN. Minimally invasive resection of rolandic cavernomas in children using a novel navigable tubular retractor system. Presented at: 13th Annual Angioma Alliance CCM Scientific Meeting; October 26-27, 2017; Washington, DC.
  9. Weiner HL, Placantonakis DG. Resection of a pediatric thalamic juvenile pilocytic astrocytoma with whole brain tractography. Cureus. 2017; 9(10): e1768. https://dx.doi.org/10.7759/cureus.1768

Intraoperative Tissue Collection & Preservation for Precision Medicine

  1. Alomari S, Kedda J, Malla AP, Pacis V, Anastasiadis P, Xu S, et al. Implementation of minimally invasive brain tumor resection in rodents for high viability tissue collection. J Vis Exp. 2022; 183:e64048. https://doi.org/10.3791/64048
  2. Das A, Gunasekaran A, Stephens HR, Mark J, Lindhorst SM, Cachia D, et al. Establishing a standardized method for the effective intraoperative collection and biological preservation of brain tumor tissue samples using a novel tissue preservation system: a pilot study. World Neurosurgery. 2022; In Press. https://doi.org/10.1016/j.wneu.2022.01.030
  3. Watson DC, Bayik D, Grabowski M, Ahluwalia M, Mohammadi A, Lathia JD. High-dimensional analysis of spatial immune cell heterogeneity in glioblastoma reveals differences between contrast-enhancing and non-contrast enhancing tumor rims. Neuro-Oncology Advances. 2021; 3(2):ii10. https://doi.org/10.1093/noajnl/vdab070.041
  4. Zusman E, Sidorov M, Ayala, A, Chang J, Singer E, Chen M, et al. Tissues harvested using an automated surgical approach confirm molecular heterogeneity of glioblastoma and enhance specimen’s translational research value. Frontiers in Oncology. 2019; AOP. https://dx.doi.org/10.3389/fonc.2019.01119
  5. Soroceanu L, Chang J, Sidorov M, Ayala AM, Zusman EE, Dickinson LD. Tissue extraction and preservation for glioblastoma specimens used for molecular oncology and personalized therapy studies. Presented at: 2017 Congress of Neurological Surgery Annual Meeting; October 7-11, 2017; Boston MA. https://www.cns.org/education/browse-type/abstracts-and-posters
  6. Cartwright M. Towards the Development of Personalized Medicine: A Novel Tissue Preservation System for the Automation and Standardization of Brain Tumor Harvesting in a Surgical Setting. FASEB Journal. 2017: 31(1): supplement lb516. http://www.fasebj.org/content/31/1_Supplement/lb516.abstract?sid=94be4899-a0b2-491e-89e1-5189dbe511f5
  7. Kumar R, Gont A, Hanson JEL, Cheung AYL, Nicholas G, Woulfe J, et al. Isolating glioblastoma tumor initiating progenitor cells from the subventricular zone using a novel minimally invasive approach. Neuro Oncol (2014) 16 (suppl 5):v200. http://doi.org/10.1093/neuonc/nou275.15

Economic Impact and Value

  1. Johnson K, Buishas J, Tsung AJ, Spence S. MIPS for intracerebral hemorrhage decreases length of ICU stay without alteration in overall cost. Neurosurgery. 2020; 67 (Supp_1):nyaa447_355. https://doi.org/10.1093/neuros/nyaa447_355
  2. King NKK, Rao JP, Tew SW. Innovation in Hemorrhagic Stroke Management Using Minimally Invasive Parafascicular Surgery. NNI White Paper. Singapore: National Neuroscience Institute; 2018. https://www.subcorticalsurgery.com/spotlight-on-healthcare-economics/
  3. Coppens J. Minimally Invasive Parafascicular Surgery (MIPS) in ICH: Economic Argument for Early Surgery. SSG White Paper. Subcortical Surgery Group; 2018. https://www.subcorticalsurgery.com/spotlight-on-healthcare-economics/
  4. Young FL, Cartwright MM. Inclusion of a minimal access surgery device system into a pilot neurosurgical enhanced recovery after surgery (ERAS) protocol. Poster presented at: 2017 Congress of Neurological Surgeons Annual Meeting; October 7-11, 2017; Boston, MA. https://www.cns.org/education/browse-type/abstracts-and-posters
  5. Norton SP, Dickerson EM, Kulwin CG, Shah MV. Technology that achieves the Triple Aim: an economic analysis of the BrainPath approach in neurosurgery. ClinicoEconomics and Outcomes Research. 2017;9: 519-523. https://doi.org/10.2147/CEOR.S133623