Tumors and Cysts via Ventriculoscope

Solution: Myriad NOVUS can be used with a ventriculoscope for vascular, large and fibrous IV lesions where one might traditionally take a microscopic approach.

Myriad NOVUS offers the following benefits:

• Only automated resection tool that fits down the channel of a ventriculoscope.
• Cutting capability allows surgeons to address more fibrous lesions.
• Automated variable aspiration controlled by the surgeon with direct visualization of suction aperture and tissue being resected.⁸
• Advancement knob allows surgeon to extend aperture without moving the handpiece and provides user with the ability to safely reach deeper into the cavity.

Solution: Minimally invasive burr hole approach into the ventricles.

• Multifunction design of the Myriad NOVUS allows for minimal instrument exchange, facilitating effective tumor resection through minimal access corridors.
• Non-heat generating device allows cannula shaft to be placed on adjacent tissues while in operation without damage to tissue or critical structures.

Solution: Automated tissue resection with Myriad NOVUS.

• Myriad NOVUS adds automation to ventriculoscope where it wasn’t available before which may enable higher GTR rates.
• Myriad NOVUS is ideal resection tool when using the ventriculoscope due to the side mouth aperture.
  • This has shown safety and effectiveness in removing large and fibrous lesions without impeding visualization.⁵

Solution: Mechanical and non-ablative/non-thermal cyst resection with Myriad NOVUS in conjunction with NICO Fluid System™ (NFS).

• Myriad NOVUS offers the following benefits:
  • Mechanically resects tissue with clean cuts which does not disturb substrate tissue.
  • Safe near adjacent neurovascular structures.⁹
  • Negligible thermal damage.⁸
  • Visualization of resection site with side mouth aperture.
  • Protects healthy and eloquent tissue with foot plate which allows only the aperture to be placed in contact with the intended tissue to be removed.
  • Ability to dial down the aspiration level on the console to build a comfort level with the Myriad NOVUS’s aspiration capabilities.¹⁰

Solution: Increased efficiency with automation using Myriad NOVUS and NFS.

• Myriad NOVUS offers the following benefits:
  • Potentially decreased operating time and operative fatigue due to automation.⁶
  • Multifunction design allows for minimal instrument exchange.¹²
  • Can be mechanically attached to the ventriculoscope which improves the ergonomics of the procedure for the surgeon and frees surgeon’s other hand for other tasks.
  • 360-degree aperture rotation allows movement of the aperture without the need to rotate the wrist, offering ergonomic control and minimizing fatigue.
  • One minute set-up time.

Solution: Automated and standardized intraoperative tissue harvesting and biological preservation with NICO Automated Preservation System (APS).

• Closed-capture system provides real-time, immediate refrigeration for desired thermal conditions.
• Ability to infuse/perfuse tissue creates the desired biological environment, which may aid tissue hydration.
• Heterogeneity of abnormalities can be accounted for due to increased quantity of tissue obtained.
• Enables the ability to capture and annotate tissue with correlation to specific intratumoral location for potential further advancement in personalized medicine.

Solution: Ability to safely create a large opening.

• Automated variable aspiration controlled by the surgeon with direct visualization of suction aperture.⁹
• Ability to dial down the aspiration level on the console to build a comfort level with the Myriad NOVUS.¹⁰

Solution: Smooth, clean-cut fenestration with Myriad NOVUS.

• Myriad NOVUS mechanically resects tissue with clean cuts which does not disturb substrate tissue.
• Once surgeon removes his foot from foot pedal, the aspiration stops immediately and Myriad NOVUS remains in open mouth position.

Patients have larger ETV defect size (28.21mm vs 11.25mm) on follow-up when NICO Myriad was used⁵